Monday, March 9, 2009

E-tegrity Results

I called the lab in CA late Fri afternoon to get a status on my e-tegrity results. Turns out they were ready Thur but no one had faxed them out. They would not give me the results due to Hippa laws. That still urks me; I requested the test, I paid for it, I had half my uterus ripped out for it, and I can't even get my own results? While on the call, the lady told me she just faxed the results to CCRM and my ob/gyn. But what good would that do, both places were closed and I would have to wait till Monday, ugh. I emailed CCRM right away hoping that maybe someone would call me Sat, but no word. I find out today that neither CCRM nor my ob/gyn has rec'd the results, double ugh! So CCRM called and got the results for me.

Here are the result possibilities from e-tegrity's website:
There are three typical patterns:
1. Beta-3 integrin POSITIVE with an “in-phase” endometrium is a normal pattern of expression.

2. Beta-3 integrin NEGATIVE with an “out-of-phase” endometrium occurs in a patient with Luteal Phase Defect; following treatment the patient is advised to undergo a repeat biopsy to confirm diagnosis.

3. Beta-3 integrin NEGATIVE in a patient with a normal “in phase” endometrium is associated with unexplained infertility, minimal or mild endometriosis, or hydrosalpinx.

The E-tegrity test:
Identifies endometrial quality
Determines Beta-3 integrin presence
Provides a histologic evaluation of the endometrium

My results came back positive and in-phase!!!! Wahooo!!! I am so so so so happy!

[Click photo for larger view]

So what I conclude from this is that my implantation failure was due to either abnormal embryos (all 8 of them) or more probable my crazy e2 levels during stims, which btw were IVF#1: 6867 IVF#2: 9029 IVF#3: 6045. During a natural cycle, e2 peaks at 200-600, so it would totally make sense that that high of an e2 level could definitely disrupt the uterine environment. So no more fresh transfers for me again, ever!

I also conclude that my inability to conceive naturally is most likely due to very weak sperm that are attacked by antisperm antibodies. Kerry developed ASAs from having a vasectomy.

Now I feel free to finally make a plan... though at this time, I have no clue what that is.

On a completely different note, I'm miserable. I got food poisoning last night. I had sour stomach all day Sun and by bed time, as I went to brush my teeth, I become violently ill. I dropped to the ground, was instantly drenched in sweat and was shaking uncontrollably. I drug myself to the toilet just in time as I knew something was going to explode, I just didn't know which end. I had bad diarrhea, sorry if that was TMI. When I leaned forward, I was about to throw up, so I had to lean back, but then I was slipping off the toilet because my legs were so sweaty. Kerry came in, held me up and put towels under my legs so I would stop sliding. My body was spasming really bad so I had no control over myself. My entire body tingled like it had fallen asleep, my wrists and hands painfully locked up. Kerry tried to straighten out my wrists and separate my fingers, but they wouldn't release, it was like a massive charlie horse from hell. Then my feet and face went numb and caused my speech to slur. I had to get to the ground, fast. Kerry insisted on wiping my butt as my hands were useless. He said, "now it's front to back right?", gotta love him! He helped me to the ground, covered me in towels and put a heater on me. He layed there on the bathroom floor with me for a half an hour massaging my hands trying to get them to release.

Anyone ever experience their wrists/hands locking up? It was so strange! Kerry thinks it was from the chemical that causes your stomach/intestines to convulse to get rid of the bad stuff.

I'm doing much better today, but feeling really weak, exhausted from no sleep and running a fever. I just have to say, do I not have an amazing husband or what! I teared up knowing that he will always take care of me and I know I can always count on him. I can't wait for him to help me through labor and delivery... someday... someday...

PS... thank you MLG for the sisterhood award, that was very sweet of you!


  1. I just KNEW with all my heart that the test would be "normal". I am also buying into your e2 theory.

    Wow....what a husband you have is right!! It would be a cold day in "you know where" before Scott would wipe my butt.....Oh my Lord!!! I'm so glad you're feeling better and how scary about the tensing up & numbness thing....

    love ya!

  2. YIPPEE!!!!! Looks like we'll have something else to celebrate in NOLA next week. I knew your test had to come out positive. Looks like we're ready for a fun downhill scream on this old roller coaster of ours.
    Love ya and look forward to seeing you all next week.


  3. I am so glad your results came out normal. So happy! I am sorry that you got struck with a bad case of food poisoning..sounds terrible. Hope you are resting and staying hydrated.

  4. Great news on the test results!
    Awful news on the food poisoning, that really sounds horrible. Take care of yourself, you've got a great nurse there!

  5. I'm just estactic with your test results, and I know you are anxious to figure out what your plan is....just work on getting better from the tramatic experience of last night. glad your feeling better today. Can't wait to see you next week.

  6. Woohoo, congrats on the biopsy results. I did that test too and was so incredibly relieved when it came back normal. One step closer and one less thing to worry about, right? Phew!

    OMG, your food poisoning sounds awful. Yikes! I hope you feel 100% v soon. Take care of yourself.

  7. I love the new look of your blog. The bees are so cute. And I'm really pleased to hear about your results.
    That food poisoning incident sounds awful. You poor thing!

  8. I am so glad to hear about your test results! I think you are absolutely right about the high e2 levels - I think Mamasoon said that Dr. Sch made some comment about maybe that being the real reason that CCRM's CGH rates and DE rates are so high - no stimming beforehand. Lets all hope that is the case!!!

    That food poisoning sounds awful! I did have my wrists seize up like that once (Brett had to keep massaging them at night to try to release them) but it was from Cipro antibiotics (its happened to my twice now). I have no idea what else would cause it! Kerry sounds very caring - you are a lucky girl. Now, go feel better and take care of each other!!!

  9. what a super cute background to your blog!!

    I am sorry you are so sick. it sounds so so so HORRIBLE. What a sweet husband you have. I hope you feel better tomorrow.

  10. YAY! For your test results! I am so glad that you have a plan, at least in the making.
    Yuck about your food poisoning, that is awful! You have such a sweet hubby!
    You are welcome for the award, I got to recognize a local sister :)

  11. I'm so happy to hear that your E-tegrity test came back normal. Yay for that! In talking with Dr. Schoolcraft after my bfn from my July cycle, he did mention to me about ET in a FET cycle has been showing more promising results. So maybe you're onto something...

    I'm sorry to hear that you got so violently ill. Goodness gracious, that must've been awful for you! I got food poisoning a few years ago and I ended up hallucinating something fierce, even scared the daylights out of DH. I ended up going to the emergency room, where the first thing they did was a pg test, even thought I protested - yeah right, like we'd ever get pg on our own. They gave me an anti-nausea shot and sent me on my way home. It turns out that I ate something really bad from a can of food that my mom gave me from the local oriental market.

  12. Yay on good results!!

    And I'm so sorry you were so sick! I hope you feel better very soon - that episode sounds terrible! Kerry sounds awfully sweet!

    BTW - do you live in the bay area? That lab seems to be right here, by where I live!! We can meet up if you're here!

  13. Hey Jill! Glad to see you got good results from your test!! That is awesome. So happy for you.
    I hope that food poisoning didn't last long - it sounded horrible. Hope you are feeling good by now and able to think about your next steps in the journey...
    Love and God Bless :-)

  14. Yay for the good Beta 3 test results. Boo for the food poisoning but even though it was a terrible experience, your DH was just a star. I teared up reading about how he took care of you - he sounds like a wonderful, wonderful man. I hope that the episode of food poisoning has passed and that you feel better now.


Thank you for your comment! Hugs, Kerry and Jill